A postdoctoral scholar position is available for qualified and motivated researchers for The X. William Yang Lab to be a member of a collaborative research team to study the neurocircuitry of opiate addiction. S/he will work on a project supported by the Center for Study of Opioid Receptors and Drugs of Abuse (CSRODA) to study the molecular and signaling pathways of the basal ganglia that may be involved in the reward and aversive behaviors that contribute to opiate addiction.
1. Design and perform mouse genetic experiments for opiate addiction and aversive learning:
a. Perform and analyze behavioral testing (e.g., passive avoidance, CPA, instrumental conditioning, etc.) in knockout and transgenic mouse lines
b. Perform neuropathological, biochemical, and transcriptional studies in mice.
c. Perform stereotaxic surgeries in mice
2. Dissect/collect tissue and perform RNA extractions for RNA-seq; design and perform experiments for subsequent validation of transcriptional studies.
3. Manage large mouse colonies, including setup breeding and genetic crosses, weaning, and perform genotyping.
4. Analyze results and prepare manuscripts for scientific publications.
5. Assist the PI in grant writing and preparation to obtain extramural funding and project progress reports.
The position requires a Ph.D. in one of the following fields: neuroscience, mouse genetics, pharmacology, psychology, or physiology, and working experience in mouse behavioral studies and molecular genetics. The individual should have demonstrated background, preferably publications, to show a track-record in cell signaling, mouse genetics (especially management and breeding of complex genetic mouse lines), rodent behavioral and neuropathological studies, and rodent surgeries. Computer skills should include proficiency in productivity software (Office, Excel, Powerpoint, Photoshop/Illustrator) and statistics software. Experience in molecular biology, transcriptional studies, confocal microscopy, and quantitative image analyses is preferred but not required. The person should be highly motivated, independent, organized and detail-oriented, have good verbal and written communication skills in English, and work well in a highly collaborative environment/project. Experience supervising others in research is also preferred.
Applicants should e-mail their CV and references to Dr. Chris Park firstname.lastname@example.org
Posted on: 7/11/18